The concept of laser toning (low fluence, multipass technique, multiple sessions at weekly intervals) is based on the proposed novel theory of subcellular selective photothermolysis. The ultrastructural changes within melanosome were studied using transmission electron microscopy. A reduction in the dendrites of epidermal melanocytes(pigment cells) was seen following laser treatment. Laser treatment caused selective photothermolysis (destruction) on Stage IV melanosomes, wherein the melanocytes remained intact and only the melanosomes were destroyed.
They concluded that the laser toning was an effective method for treating melasma through subcellular- selective photothermolysis. Traditional treatments result in destruction and death of pigment-containing cells. In response to which inflammation follows and results in repigmentation and recurrence or postinflammatory hyperpigmentation (PIH). Since fluence used is very less and there is no cell death, inflammation and heating is minimum, thus reducing the chances of recurrence.
Monday - Saturday: 10:00 AM - 7:00 PM Sunday: Closed
The concept of laser toning (low fluence, multipass technique, multiple sessions at weekly intervals) is based on the proposed novel theory of subcellular selective photothermolysis. The ultrastructural changes within melanosome were studied using transmission electron microscopy. A reduction in the dendrites of epidermal melanocytes(pigment cells) was seen following laser treatment. Laser treatment caused selective photothermolysis (destruction) on Stage IV melanosomes, wherein the melanocytes remained intact and only the melanosomes were destroyed.
They concluded that the laser toning was an effective method for treating melasma through subcellular- selective photothermolysis. Traditional treatments result in destruction and death of pigment-containing cells. In response to which inflammation follows and results in repigmentation and recurrence or postinflammatory hyperpigmentation (PIH). Since fluence used is very less and there is no cell death, inflammation and heating is minimum, thus reducing the chances of recurrence.